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Cathepsin G (CTSG) (Native Protein)
from  biotez
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30 600 302 Catalog number

25 µg Size

224 € Price

More details

Protein type

Native

Protein subtype

EC 3.4.21.20

Protein family

Member of the peptidase S1 protein family

Protein description

CTSG is a serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride.

Research area interests

Diseases associated with CTSG include Papillon-Lefevre Syndrome and Cutaneous Mastocytosis. Among its related pathways are Peptide ligand-binding receptors and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics.

Package form

liquid

Tested applications

Characterization of structure and function; Screening of inhibitors; Standard in enzymatic and immunologiacal assays

Other names

CTSG

Peptide sequence

MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL

Available target modification

No

Expression system

Human Blood

Product Subtype

full length

Active form?

Yes

Tag

untagged

Contents

50 mM acetate buffer pH 5.5, 250 mM NaCl

Protein purity

>95%

Molecular weight

29 kDa

UniProt number

P08311

Gene number

1511

Abbreviation

CTSG

Full name

cathepsin G

Other desciption

Cathepsin G (EC 3.4.21.20) from human neutrophils. Prepared from whole human blood, shown to be non-reactive for HbsAG, antiHCV, anti-HBc, and negative for anti-HIV1 & 2 by FDA approved tests.

Purification

Mentioned in the data sheet

PubMed citations

See the data sheet

Warnings

For Research Use only.

Shipping conditions

dry ice

Storage condition

Store at -70°C

Technical datasheet

Contact us to receive the datasheet

Gene

CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.